I’m Luca Businaro, a micro and nanotechnology scientist with over 20 years of experience in developing top-down fabrication techniques and their application in several research and industrial fields. My primary scientific interest is the application of nanophotonics and microfabrication techniques to recreate and study cell systems’ interaction, particularly the immune system-cancer and glia-neuron interactions, on chip. I have been a pioneer in the field of organs-on-chip, developing artificial environments to co-culture different cell populations and reconstitute complex biological systems to be studied “under the microscope.”

In addition to my work on organs-on-chip, I am also interested in the interaction among on-chip and in-silico biological models. I believe that a multi-disciplinary approach is necessary to fully understand biological systems, and the combination of experimental and computational models can provide a deeper insight into their complexity.

As the co-founder and president of the Italian Organ-on-Chip Society, committed to promoting the development and application of organs-on-chip technologies in Italy and beyond. I am also the scientific coordinator of the CNR-University Campus Biomedico Joint Lab “Nano4Life” and a member of the inter-institute group “Tech4Bio,” both initiatives intended to help the development of the interaction with industry.

Throughout my career, I have been involved in several research projects at EU, national, and regional level and have authored numerous publications on photonics, nanofabrication, microfluidics and cells-on-chip technologies.




Gli organ-on-a-chip e i modelli matematici per studiare il corpo umano

Research Activity

Microfluidics, lab-on chip and spectroscopy techniques for agrifood and life sciences, Organs-on-chip

Research Unit


Contact details

luca.businaro at