Microfluidics, lab-on chip and spectroscopy techniques for agrifood and life sciences

ORGAN-ON-CHIP: Advanced in-vitro functional immune system models for personalized medicine (autoimmune, infectious and neoplastic disease applications). Development of an experimental ecosystem to reproduce and measure immune system response to diverse pathological conditions exploiting microfluidics, advanced microscopy and advanced image and data analysis (Luca Businaro, Adele De Ninno, Francesca Romana Bertani, Annamaria Gerardino)

Keywords: Microfabrication, Organs on chip, Advanced data analysis, Artificial intelligence

Founders of the Italian Society for Organ-on-Chip      https://www.siooc.it/



MULTIMODAL SPECTROSCOPY FOR AGRIFOOD: development of innovative tools to determine the quality and safety characteristics of food, both as a raw material and during the various processing stages exploiting the combination of different range spectroscopies (near-infrared, visible and fluorescence) and imaging with chemometric models. Integration of miniaturized spectrometers and camera in portable instruments for on-field nondestructive measurements. (Francesca Romana Bertani, Annamaria Gerardino, Luca Businaro, Adele De Ninno).

Keywords: multimodal spectroscopy and imaging, chemometrics, machine learning based models

PhasmaFOOD platform (developed with the H2020 PhasmaFOOD)



http://www.tech4biolab.eu       Tech4Bio group, interdisciplinary group based at ARTOV Research Area in Rome

http://www.biophysicsatrome.org/      Biophysics@Rome, a biennial symposium held with the patronage of SIBPA (Italian Society of Pure and Applied Biophysics) organised by Tech4Bio group

People involved:

Luca Businaro

Annamaria Gerardino

Francesca Romana Bertani

Adele De Ninno

Andrea Notargiacomo

Marialilia Pea

Ennio Giovine



  • “ITHACA – Integrazione di Tecnologie High-throughput per lo screening veloce di AntiCorpi per terapie Antitumorali”, POR FESR Lazio 2014-2020 – “Progetti Strategici 2019”, n. PROT. A0320-2019-28177 (2019-2022)
  • “PERSEO – multidisciplinary Platform for nEuRodegenerative diSease drug tEsting On chip” POR FESR Lazio 2014-2020 – “Gruppi di Ricerca” n. PROT. A0375-2020-36656 (2021-2023)
  • PNRR- Ecosistema dell’Innovazione ROME TECHNOPOLE (ECS 00000024) (2022- 2025)
  • SPECTRAFOOD – “Sviluppo di un Dispositivo portatile integrato per la valutazione spettroscopica multimodale non invasiva della qualità delle materie prime alimentari” – POR FESR Lazio 2014-2020 –  “Gruppi di Ricerca” n. PROT. A0375-2020-36643 ( 2021-2023)
  • “MICROSYSTEMQ – Microsistema intelligente per monitoraggio di qualità di cellule, lieviti e sementi “ POR FESR Lazio 2014-2020 – “Gruppi di Ricerca” n. PROT. A0375-2020-36727 (2021-2024)


Research units: